GLP-1 Guides

From the 0.25mg starting dose to the 2.4mg maintenance dose — why the escalation exists and what happens at each step.

Both contain semaglutide, both are made by Novo Nordisk — but they're approved for different things and prescribed at different doses.

Tirzepatide and semaglutide both produce significant weight loss. Here's what the SURMOUNT and STEP trials actually found — and what the data means.

The 5-day rule for semaglutide, the 4-day rule for tirzepatide, and the one thing you should never do after a missed dose.

What to log, how often to weigh yourself, how to set a realistic goal weight, and what a trend chart tells you that a single weigh-in can't.

Where to inject, why rotation matters, how to avoid lipodystrophy, and technique tips for weekly subcutaneous injections.

The STEP 1, 2, 3 and 4 trials explained — what the averages actually mean and why individual results vary so much.

Nausea, constipation, fatigue — what to expect, when it gets better, and when to call your prescriber.

Appetite suppression often starts within weeks. Visible weight loss takes longer. Here's the realistic week-by-week timeline.

The SURMOUNT-5 head-to-head trial data, the mechanism difference, and what it means for choosing between Wegovy and Mounjaro.

Why plateaus happen on Wegovy, Ozempic and Mounjaro, how long they last, and the practical steps that actually help.

How these medications work for people with T2D, the HbA1c evidence, cardiovascular benefits, and why weight loss is typically lower in this population.